LDL Physical and Chemical Properties in Familial Combined Hyperlipidemia
نویسندگان
چکیده
منابع مشابه
Plasma triglyceride and LDL heterogeneity in familial combined hyperlipidemia.
Familial combined hyperlipidemia (FCHL) is a genetic disorder characterized by increases in plasma cholesterol and/or triglyceride, elevated apolipoprotein B, and heterogeneous low density lipoprotein (LDL). To examine the relation between plasma triglyceride concentrations and LDL heterogeneity, 13 hypertriglyceridemic FCHL patients with a predominance of small LDL (LDL subclass phenotype B) w...
متن کاملPravastatin effectively lowers LDL cholesterol in familial combined hyperlipidemia without changing LDL subclass pattern.
Familial combined hyperlipidemia (FCHL) is the most common genetic lipid disorder among young survivors of myocardial infarction. Elevations of plasma total and low-density lipoprotein (LDL) cholesterol and the prevalence of small, dense LDL particles are both involved in the high coronary risk of FCHL patients. We investigated the ability of pravastatin to favorably correct plasma lipid and li...
متن کاملCarotid intima-media thickness in familial combined hyperlipidemia and LDL size.
In the article by Liu et al, as part of the European Multicenter Study on Familial Dyslipidemia (EUFAM),1 148 asymptomatic familial combined hyperlipidemia members from 38 Finnish families were investigated for low-density lipoprotein (LDL) particle size, LDL susceptibility to oxidation, and the association of these LDL properties with carotid intima-media thickness (IMT) determined by ultrasou...
متن کاملPlasma lipoproteins in familial combined hyperlipidemia and monogenic familial hypertriglyceridemia.
Plasma lipoprotein concentration, composition, and size were evaluated in two common familial forms of hypertriglyceridemia and compared with those in normal subjects. The very low density lipoproteins (VLDL) were triglyceride-enriched in familial hypertriglyceridemia (triglyceride/apoprotein B ratio: 25.7 +/- 8.9) as compared to normal (9.6 +/- 12.2, P < 0.001) or familial combined hyperlipide...
متن کاملPulse wave velocity in familial combined hyperlipidemia.
BACKGROUND In the present cross-sectional study we investigated whether familial combined hyperlipidemia (FCH) is associated with an increased arterial wall stiffness, and whether measures of arterial wall stiffness in FCH family members could contribute to cardiovascular risk stratification. METHODS Ninety-eight subjects with FCH and 230 unaffected relatives filled out a questionnaire about ...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 1995
ISSN: 1079-5642,1524-4636
DOI: 10.1161/01.atv.15.4.452